Brown the ground beef in a large skillet over medium heat with the onion, green bell pepper, red bell pepper, garlic, salt, and pepper until the beef is fully cooked.
Drain any excess grease.
Add the Worcestershire sauce, tomato sauce, Italian seasoning, water, and macaroni. Stir well.
Bring to a boil, then reduce the heat to low.
Cover and simmer for 15 minutes, stirring occasionally, until the macaroni reaches your desired tenderness.