In a large skillet over medium-high heat, brown ground beef until fully cooked and no longer pink. Drain any excess grease and return the beef to the skillet.
Stir in minced garlic and cook for 1 minute, until fragrant.
Add tomato sauce, onion powder, cumin, chili powder, salt, and black pepper. Stir well to combine and cook for 2–3 minutes over medium-high heat. Remove from heat and set aside.
Heat a separate skillet over medium-high heat.
Place burrito-size tortilla in the skillet. Add one-fourth of the beef mixture to half of the tortilla and top with shredded Colby Jack cheese.
Fold the tortilla in half and cook for 2–3 minutes, until the bottom is golden brown.
Carefully flip and cook for an additional 2–3 minutes, until the other side is golden brown and the cheese is melted.
Transfer to a plate and repeat with the remaining tortillas, beef mixture, and cheese to make more quesadillas.
Slice each quesadilla into 4 pieces, serve warm, and enjoy!
Notes
Refrigerate the leftovers in an airtight container for up to 4-5 days.